Bioreactors

Multi-channel bioreactor RTS-8

Bioractor with real time biomass, pH and pO2 measurement

RTS-8 is a personal bioreactor that uti lizes patented ReverseSpin® technology that applies non-invasive, mechanically driven, low energy consumption, innovati ve type of agitation where cell suspension is mixed by the singleuse falcon bioreactor tube rotation around its axis with a change of direction of rotation motion resulting in highly efficient mixing and oxygenation for aerobic cultivation. Combined with a nearinfrared optical system it is possible to register cell growth kinetics non-invasively in real time.

Applications

  • Fermentation real time growth kinetics
  • Clone candidate screening
  • Protein expression
  • Temperature stress and fluctuation experiments
  • Media screening and optimization
  • Growth characterization
  • Inhibition and toxicity tests
  • Strain quality control

 

3 - 50 ml Tubes

Part Number: LTF00259

Features of multi-channel bioreactors

  • Parallel cultivation enables to save time and resources for bioprocess optimization
  • Individually controlled bioreactor accelerates optimization process
  • Possibility to cultivate microaerophilic and obligate anaerobic microorganisms (not strict anaerobic conditi ons)
  • Reverse–Spin® mixing principle enables non-invasive biomass measurement in real time
  • Near-infrared optical system makes it possible to register cell growth kinetics
  • Free of charge soft ware for storage, demonstration and analysis of data in real time
  • Compact design with low profile and small footprint for personal application
  • Temperature control for bioprocess applications
  • Active cooling for rapid temperature control, e.g. for temperature fluctuation experiments
  • Task profiling for process automatization
  • Cloud data storage to remotely monitor the process of cultivation while at home or using a mobile phones

Software RTS-8

  • Real–Time cell growth logging
  • 3D graphical representation of OD or growth rate over time over unit
  • Pause option
  • Save/Load option
  • Report option: PDF and Excel
  • Connect up to 12 units (recommended) simultaneously to 1 computer
  • Remote monitoring option (requires internet connection)
  • Cycling/Profiling options
  • User manual calibration possibility for most cells

Benefits RTS-8

RTS mixing principle has a number of advantages, e.g. automatic balancing, defoaming single-use, etc., but one of the more important points is that, due to the individual rotation principle and thermostating of each bioreactor tube, different conditions for supporting the temperature (from 4 to 70°C) and aeration conditions can be applied (from anaerobic to aerobic).

 

 

Measurement range0 – 100 OD600
Measurement wavelength (λ)850 ± 15 nm
Light sourceLaser
Measurement periodicity per hour1-60
Temperature setting range+4°C – +60°C
Temperature control ratge15°C  below ambient up to +60°C
Heating/cooling rate0.5°C/min
Sample volume3 – 50 ml
Speed control range50 –  2700 rpm
Max. number of units connected with the sofware12 (recommended)
DisplayLCD
Minimum PC requirements

Intel/AMD Processor, 1 GB RAM, Windows XP* /Vista/7/8/8.1,
2.0 USB port

optimal PC requirementsIntel/AMD Processor, 3 GB RAM Windows XP*/Vista/7/8/8.1/10, USB 2.0 port
*not guaranteed because OS not supported by producer
Dimensions (WxDxH)330 x 580 x 320 mm
Weight15 kg
Internal power supplyInput AC 240 V 50/60 Hz; Output DC 12 V

O2 sensor

Range0 – 100%
Accuracy± 0.01% O2 at 0.21%,
± 0.1% O2 at 20.9%
Drift< 0.015% O2 pro Tag
Temperature rangeup to 40°C

pH sensor

RangepH 4.0 – pH 8.5
Accuracy0,05 pH bei pH 7 with onepoint calibration,
± 0,10 pH bei pH 7 with precalibration
Drift< 0.005 pH per Day
Temperature range pHup to 40°C

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